Intangiriro Yuzuye
3,4 - Dihydro - 2H - pyran (DHP, CAS 110-87-2) ni intera ndende cyane kandi igereranya muri synthesis organique, cyane cyane izwi kubera uruhare rwayo mu kurinda inzoga. Nka eteri igizwe nabantu batandatu badahagije, DHP ikora ether ya tetrahydropyranyl (THP) iyo ikozwe na alcool mugihe cya acide. Izi ngamba zo gukingira ningirakamaro muri synthesis ya multistep kugirango hirindwe ibisubizo bidakenewe kurubuga rwa hydroxyl mugihe ukomeza guhuza na reagent yibanze na nucleophilique.
DHP ni ibara ritagira ibara, rito - amazi atetse akozwe na hydrogenation ya dihydropyran cyangwa furfural ishobora kuvugururwa. Imiterere yacyo ya vinyl ether ituma ihinduranya kandi igahindura ihinduka rya molekile kama, bigatuma iba ingenzi muri laboratoire ya chimie ya kijyambere hamwe nubuvuzi bwa R&D.
Ibisobanuro birambuye
| Izina ryibicuruzwa | DHP muri sythesis organic CAS 110-87-2 |
| URUBANZA OYA. | 110-87-2 |
| Synonyme | DHP |
| Inzira ya molekulari | C5H8O |
| Kode ya HS | 2932999099 |
| Imiterere |  |
Ibisobanuro
|
Ibintu |
Bisanzwe |
|
Kugaragara |
Amazi adafite amabara meza |
|
Isuku (%) |
Biruta cyangwa bingana na 98.5 |
|
Ubushuhe (%) |
Ntibiri munsi cyangwa bingana na 0.25 |
|
THP (%) |
1.3 max |
| Ubucucike (g / cm³) | 0.922 |
Imikoreshereze & Core Imikorere muri Synthesis Organic
- THP Ether Imiterere (Kurinda Inzoga):
DHP ikora hamwe na alcool yibanze niyisumbuye imbere ya catisale ya aside (urugero, p - TsOH, HCl) kugirango ikore THP ethers. Ibi birinda amatsinda ya hydroxyl okiside, acylation, cyangwa alkylation mubyiciro bikurikira.
- Gutoranya Guhitamo:
Amatsinda ya THP akurwaho byoroshye akoresheje aside yoroheje (urugero, acide acetike mumazi cyangwa TFA), itanga imitekerereze myiza mukurinda ingamba zitsinda.
- Porogaramu muri Synthesis ya Molecule igoye:
Ibicuruzwa bisanzwe:THP ethers ituza abahuza ibikorwa byinshi.
Peptide na karubone:Kurinda guhitamo hydroxyl - ifite iminyururu kuruhande hamwe na alcool ya sukari.
API synthesis:Ikoreshwa mu biyobyabwenge nka erythromycine, steroid, na alkaloide.
- Inyungu zihamye:
THP ethers ihagaze neza mubihe byibanze, bigabanya, kandi byoroheje bya okiside, byemerera reaction nka Grignard yongeyeho, shingiro - yazamuye kanseri, hamwe nicyuma - catalize.
Ubushobozi bw'umusaruro
Byuzuye - Impamyabumenyi Yumutekano
Basabwe Kuringaniza Imiterere ya Porogaramu
Multi - kurinda intambwe ya alcool mubicuruzwa bisanzwe
Imiterere ya THP ethers muri chimie ya karubone
Peptide synthesis irimo serine, threonine, hamwe no kurinda tirozine
Chimie ya Grignard na organolithium irimo hydroxyl - irimo ibanziriza
Ibiyobyabwenge bigizwe hagati aho hydroxyl masking ari ngombwa
Gupakira
Iraboneka muri: 180 kg ingoma, 1L cyangwa 5L amacupa yikirahure yo gukoresha laboratoire
Ibibazo
Ikibazo: Kuki DHP ihitamo kurinda inzoga?
Igisubizo: Irakora mubihe byoroheje, itanga ituze ryiza kuri THP ethers mubihe byibanze cyangwa bidafite aho bibogamiye, kandi ikurwaho byoroshye mugihe ubishaka.
Ikibazo: Ese DHP ikwiranye na synthesis yimikorere ikora?
Igisubizo: Yego. Imyitwarire yayo iteganijwe kandi ihujwe nuburinzi busanzwe - protocole de prototection ituma biba byiza kuri automatike kandi ndende - kwinjiza synthesis.
Ikibazo: DHP irashobora gukoreshwa mubipimo - hejuru?
Igisubizo: Rwose. DHP iraboneka kubwinshi kandi ikoreshwa mu kilo - kugeza kuri - toni mu nganda zimiti n’imiti myiza.
Ibisobanuro
|
Ibintu |
Bisanzwe |
|
Kugaragara |
Amazi adafite amabara meza |
|
Isuku (%) |
Biruta cyangwa bingana na 98.5 |
|
Ubushuhe (%) |
Ntibiri munsi cyangwa bingana na 0.25 |
|
THP (%) |
1.3 max |
| Ubucucike (g / cm³) | 0.922 |
Ibirangantego: dhp muri synthesis organique, Ubushinwa dhp mubikorwa bya synthesis organique, abatanga, uruganda
